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The Influence of the Latest Scientific Research Results of the International Authoritative Journal on the Breeding of Guangming No.2

Dec 24, 2025

Publication Overview

On November 18, the Institute of Animal Sciences of the Chinese Academy of Agricultural Sciences published a significant research paper in the prestigious international journal Advanced Science. This study marks the first systematic analysis of metabolic biomarkers and genetic regulatory mechanisms associated with mortality risk in white-feathered broilers. These findings provide a critical scientific basis for enhancing disease resistance and optimizing domestic breeds. The "Guangming No. 2" breed, independently developed by Guangming Bio, serves as a prime example of these findings in practice, demonstrating superior adaptability, higher survival rates, and stable metabolic health.

Industry Context

While long-term breeding has significantly improved the growth rate and production performance of white-feathered broilers, rapid growth often puts the metabolic system under high-load stress. This can lead to metabolic dysfunction and increased mortality, posing a challenge to the sustainable development of the industry.

Key Scientific Discoveries

By integrating multi-omics data through a "metabolome-genome-physiological state" analysis, the research team established a causal chain from metabolic disorder to mortality risk. The study revealed a "homeostatic remodeling mechanism" of metabolic networks under high stress. Key findings include:

  • Identification of 16 critical metabolites closely related to mortality risk, with butyric acid and L-cysteine being particularly significant.
  • Observation of metabolic pathway disruptions in high-mortality groups, accompanied by increased inflammation and decreased growth performance.
  • Genetic vs. Physiological Drivers: While genetics provide the foundation, metabolic remodeling triggered by physiological states is the primary driver of risk variance.

The Future of Breeding The industry is shifting its focus from "rapid growth" to "health, stability, and low risk". Disease resistance and metabolic homeostasis are becoming the core competitive factors for future breeds. As a nationally approved representative breed, "Guangming No. 2" prioritized health and resilience from its inception. Having won top science and technology awards and achieved the first export of grandparent stock in 2025, the breed's success validates the scientific focus on metabolic and immune stability.

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